Skip to main content
. 2020 Oct 26;21(21):7949. doi: 10.3390/ijms21217949

Figure 5.

Figure 5

Effect of HTNs 1-3 on caspase-3 activity in SH-SY5Y neuroblastoma cells after ischemia reperfusion. Bars show % LDH release after OGD (4 h) and IR (24 h), without treatment (IR alone) or treated with HTNs 1-3, PBN, and NAC, at the indicated concentrations. Values are the mean ± SEM of three experiments, each one performed in triplicate, and compared to the effect of I and IR on respective controls (red ***) or the effect of the different compounds after IR (24 h) with IR alone (red dotted line), in the absence of these compounds (black ***). Data were statistically analyzed by one-way ANOVA, followed by Holm–Sidak as test post hoc. * p < 0.05, ** p < 0.01, and *** p < 0.001. UAF = arbitrary fluorescent units.