Table 1.

Neuroprotective effect of HTNs 1-3, PBN, and NAC against neurotoxicity induced by oligomycin A/rotenone in human neuroblastoma SH-SY5Y cells.

The estimation of EC₅₀ (μM) and maximal activities (% neuroprotection) values were performed by a weighted nonlinear regression of minimum squares using logistic curves, as is described in the “Statistical Analysis” section of “Neuroprotection Assessment Assays”. Values are the mean ± S.E.M. Data analysis was carried out with SigmaPlot v.12., and ANOVA one-way to get the significant statistics of HTNs with respect to PBN. Differences are statistically significant when p ≤ 0.05. Differences are statistically significant when p ≤ 0.05. * p < 0.05, ** p < 0.01, and *** p < 0.001, ns = non-significant (ANOVA one-way, followed by Holm−Sidak analysis as test post hoc).