FDA |
Food and Drug Administration |
JAK3 |
Janus kinase 3 |
EGFRK |
Epidermal growth factor receptor kinase |
ATP |
Adenosine triphosphate |
SRC |
Proto-oncogene tyrosine-protein kinase Src |
Boc |
tert-Butyloxycarbonyl protecting group |
TFA |
Trifluoroacetic acid |
DCM |
Dichloromethane |
DMF |
Dimethylformamide |
TEA |
Triethylamine |
PPA |
Polyphosphoric acid |
THF |
Tetrahydrofuran |
DMSO |
Dimethyl sulfoxide |
ADP |
Adenosine diphosphate |
IC50
|
The half maximal inhibitory concentration |
Bn |
Benzyl |
Me |
Methyl |
Et |
Ethyl |
Pr |
Propyl |
Ac |
Acetyl |
GI50
|
The half maximal growth inhibitory concentration |