Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic representation of YZT-mediated UPS pathway in vivo. (A) YZT treatment significantly decreases the poly ubiquitin levels in P301S mice brain homogenate compared to the Tg-vehicle and its quantification. (B) Long term YZT treatment in 3XTg-AD mice significantly reduced the ploy ubiquitin protein levels when compared to Tg-vehicle. (C) Schematic diagram illustrating that involvement of ubiquitin proteasomal pathway in YZT-mediated degradation of tau.
