Table 1.
Demographics and clinical characteristics of all subjects.
| Healthy Controls (n = 18) | Hypothyroid (n = 18) |
||
|---|---|---|---|
| Before L-T4 | After L-T4 | ||
| Age (year) | 44.50 ± 6.13 | 43.06 ± 7.04 | |
| Sex (female/male) | 12/6 | 13/5 | |
| BMI | 23.46 ± 1.26 | 23.72 ± 1.02 | |
| Education (year) | 13.00 ± 1.49 | 13.22 ± 1.52 | |
| TSH (mIU/l) | 2.48 ± 0.84 | 95.3 ± 34.51 | 2.44 ± 0.79 |
| fT3 (pmol/l) | 4.52 ± 0.92 | 1.98 ± 0.63 | 4.74 ± 0.58 |
| fT4 (pmol/l) | 15.7 ± 3.19 | 5.96 ± 1.59 | 17.4 ± 2.09 |
| MoCA | 26.01 ± 1.60 | 23.68 ± 1.61¶ | 25.6 ± 1.91¢ |
| WMS-CR (MQ) | 124 ± 7.46 | 104 ± 11.67¶ | 122 ± 10.88§ |
| BDI-II | 3.78 ± 1.83 | 11.0 ± 2.29¶ | 3.06 ± 0.94§ |
BMI, body mass index; TSH, thyroid stimulating hormone; fT3, free triiodothyronine; fT4, free thyroxine; MoCA, Montreal Cognitive Assessment; WMS-CR (MQ), Wechsler Memory Scale-Chinese Revision (memory quotient); BDI-II, Beck Depression Inventory-II; L-T4, levothyroxine. Significant differences revealed by independent t-test between patients and controls, ¶P < 0.001; Significant differences revealed by paired t-test between patients before and after L-T4 treatment, ¢P < 0.05, §P < 0.001.