| ABC-HRP | avidin-biotin complex-horse radish peroxidase |
| ACTB | actin cytoplasmic 1 |
| AKT3 | V-akt murine thymoma viral oncogene homolog 3 |
| BBB | blood brain-barrier |
| BST2 | CD317, tethrin |
| CACNA1E | calcium voltage-gated channel subunit alpha 1E |
| CALM | calmodulin |
| CAMK2A | calcium/calmodulin-dependent protein kinase II alpha |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| cAMP | cyclic adenosine monophosphateP |
| CCL2 | C-C motif chemokine ligand 2 |
| CCL3 | C-C motif chemokine ligand 3 |
| CCL4 | C-C motif chemokine ligand 4 |
| CCR5 | C-C motif chemokine receptor 5 (gene/pseudogene) |
| CD163 | CD163 molecule, Scavenger Receptor Cysteine-Rich Type 1 Protein M130 |
| CD274 | cluster of differentiation 274, programmed death-ligand 1 |
| CD74 | CD74 molecule, HLA class II histocompatibility antigen gamma chain |
| CD80 | co-stimulatory molecule B7-2 |
| CD86 | cluster of differentiation 86, B7-2 |
| CD8A | CD8a molecule, T-cell surface glycoprotein CD8 alpha chain |
| cDNA | complementary DNA |
| CFAS | Cognitive Function and Ageing Study |
| CNS | central nervous system |
| COL6A3 | collagen type VI alpha 3 chain |
| CX3CR1 | C-X3-C motif chemokine receptor 1 |
| CYBB | cytochrome b-245, beta polypeptide |
| DAVID | Database for Annotation, Visualization and Integrated Discovery |
| DEPC | diethylpyrocarbonate |
| DSCL | deep subcortical lesions |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| EPSTI1 | epithelial stromal interaction protein 1 |
| FCER1G | Fc fragment of IgE receptor Ig |
| FCGR1A | Fc fragment of immunoglobulin gamma Fc receptor 1A |
| FCGR2A | Fc fragment of immunoglobulin gamma Fc receptor 2A |
| FGL2 | fibrinogen like 2 |
| FPR1 | formyl peptide receptor 1 |
| GABA | gamma-aminobutyric acid |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase |
| GBP5 | guanylate-binding protein 5 |
| GEO | gene expression omnibus |
| GRIA | glutamate receptor, ionotropic, AMPA |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| H&E | haematoxylin and eosin |
| HAVCR2 | hepatitis A virus cellular receptor 2 |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha |
| IFI35 | interferon induced protein 35 |
| IFI44 | interferon induced protein 44 |
| IFI44L | interferon induced protein 44-like |
| IFIT1 | interferon induced protein with tetratricopeptide repeats 1 |
| IFIT3 | interferon induced protein with tetratricopeptide repeats 3 |
| IFNAR1 | interferon alpha receptor subunit 1 |
| IGSF6 | immunoglobulin superfamily member 6 |
| IHC | immunohistochemistry |
| IKBKB | inhibitor of nuclear factor kappa B kinase subunit beta |
| IL1A | interleukin 1 alpha |
| IL1B | interleukin 1 beta |
| IRF7 | interferon regulatory factor 7 |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | interferon-stimulated gene 15 |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit), CD11c |
| IVT | in vitro transcription |
| JUN | jun proto-oncogene, AP-1 transcription factor subunit |
| KEGG | Kyoto Encyclopedia of Genes and Genomes |
| LCM | laser capture microdissection |
| LCP2 | lymphocyte cytosolic protein 2 |
| LFB | luxol fast blue |
| LY6E | lymphocyte antigen 6E |
| MAPK | mitogen-activated protein kinase |
| MHC-II | major histocompatibility complex class II |
| MRC1 | mannose receptor C-type 1 |
| MRI | magnetic resnance imaging |
| mRNA | messenger ribonucleic acid |
| MS4A6A | membrane spanning 4-domains A6A |
| MSR1 | macrophage scavenger receptor 1 |
| MX1 | MX dynamin like GTPase 1 |
| OAS1 | 2’-5’-oligoadenylate synthetase 1 |
| OAS2 | 2’-5’-oligoadenylate synthetase 2 |
| OAS3 | 2’-5’-oligoadenylate synthetase 3 |
| PCA | principal component analysis |
| PHF21A | PHD finger protein 21A |
| PI3K-Akt | phosphatidylinositol 3-kinase-protein kinase |
| PTGS2 | prostaglandin-endoperoxide synthase 2 |
| PVL | periventricular lesions |
| QC | quality control |
| REC | research ethics committee |
| RPLP0 | 60S acidic ribosomal protein P0 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 |
| RT | room temperature |
| SAMSN1 | SAM domain, SH3 domain and nuclear localisation signals 1 |
| SLAMF8 | SLAM family member 8 |
| TAC | transcriptome analysis console |
| TFEC | transcription factor EC |
| TREM2 | triggering receptor expressed on myeloid cells 2 |
| UBE2L6 | ubiquitin conjugating enzyme E2 L6 |
| USP18 | ubiquitin specific peptidase 18 |
| WM | white matter |
| WML | white matter lesions |
| XAF1 | XIAP-associated factor 1 |