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. 2020 Oct 29;25(21):5016. doi: 10.3390/molecules25215016

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Cytotoxicity of chloroform fractions of T. vulgaris (TCF) and A. lappa (ACF) towards NCI-H929 cells and peripheral blood mononuclear cells (PBMCs) as determined by the resazurin assay. (A): Cytotoxicity towards normal PBMCs. (B): The ferroptosis inhibitors (ferrostatin-1 and deferoxamine) abrogated cytotoxicity of the extracts, indicating the role of ferroptosis cell death. Control: NCI-H929 cell without ferroptosis inhibitors.