Table 2.
Cytotoxicity of different T. vulgaris and A. lappa fractions towards leukemia cell lines as determined by resazurin assay.
| T. vulgaris | A. lappa | |||||
|---|---|---|---|---|---|---|
| Fractions | CCRF-CEM | CEM/ADR5000 | CCRF-CEM | CEM/ADR5000 | ||
| IC50 (μg/mL ± SD) | IC50 (μg/mL ± SD) | D.R. | IC50 (μg/mL ± SD) | IC50 (μg/mL ± SD) | D.R. | |
| HF | 31.51 ± 1.63 | 34.02 ± 0.84 | 1.08 | 29.72 ± 1.10 | 55.93 ± 0.68 | 1.88 |
| CF | 2.13 ± 3.77 | 4.00 ± 0.15 | 1.88 | 6.75 ± 0.95 | 14.95 ± 3.28 | 2.21 |
| EF | 4.35 ± 1.18 | 24.85 ± 2.60 | 5.71 | 25.38 ± 3.29 | 29.80 ± 2.32 | 1.17 |
| BF | 28.64 ± 0.35 | 94.35 ± 4.60 | 3.29 | 30.67 ± 2.09 | 93.48 ± 4.89 | 3.05 |
D.R., degree of resistance; HF, n-hexane fraction; CF, chloroform fraction; EF, ethyl acetate fraction; BF, butanol fraction. Values are presented as the mean ± SD.