Table 3.
Cytotoxicity of chloroform and ethyl acetate fractions of T. vulgaris and A. lappa towards MM cell lines as determined by the resazurin assay.
| MM Cell Line | T. vulgaris | A. lappa | ||
|---|---|---|---|---|
| IC50 (µg/mL ± SD) | IC50 (µg/mL ± SD) | |||
| CF | EF | CF | EF | |
| MOLP-8 | 13.45 ± 3.49 | 41.63 ± 0.53 | 39.51 ± 2.30 | 56.92 ± 1.00 |
| NCI-H929 | 6.49 ± 1.48 | 25.55 ±3.78 | 21.9 ± 0.69 | 35.01 ± 0.94 |
| RPMI-8226 | 27.14 ± 0.01 | 30.17 ± 0.17 | 18.26 ± 0.26 | >100 |
| KMS-12BM | 15.28 ± 4.90 | 31.78 ± 3.46 | 22.3 ± 0.18 | 81.2 ± 1.78 |
| KMS-11 | 17.26 ± 2.48 | 35.15 ± 1.93 | 31.95 ± 2.37 | 65.04 ± 1.89 |
| L-363 | 11.28 ± 4.64 | 25.61 ± 2.21 | 46.97 ± 3.66 | 35.62 ± 0.43 |
| JJN-3 | 13.88 ± 1.19 | 30.11 ± 1.69 | 25.99 ± 0.70 | 48.00 ± 4.41 |
| AMO-I | 14.02 ± 2.64 | 35.07 ± 3.23 | 29.11 ± 1.04 | 35.02 ± 0.59 |
| OPM-2 | 6.91 ± 3.70 | 26.06 ± 0.78 | 35.63 ± 4.079 | 45.96 ± 2.49 |
MM, multiple myeloma; CF, chloroform fraction; EF, ethyl acetate fraction. Values are presented as the mean ± SD.