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The effect of L-KYN on the protein level and cellular localization of cyclin D1 (a) and CDK4 (b) in melanoma A375 cells. Immunofluorescent staining of cyclin D1 (a) and CDK4 (b) in A375 cells treated with L-KYN 5 mM for 24 h (control; not treated). Cell nuclei were labeled with cell permeable fluorescent DNA dye DraQ5. Magnification 40×.
