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. 2020 Oct 30;25(21):5060. doi: 10.3390/molecules25215060

Figure 1.

Figure 1

Natural ligands of GPCRs from Bacteria (a) and Protoctists (b). Each chemical class is highlighted with different colors. The chemical structures were found on ChemSpider website. Legend: the plus symbol means that this compound is approved by the Food and Drug Administration; ago.: agonist; ant.: antagonist; a.m.: allosteric modulator. Superscript: (I) [1]; (II) [13]; (III) [16]; (IV) [17]; (V) [18] the chemical structure shown is an example of a specific 15-keto-prostaglandin; (VI) [19].