Figure 4.
HSD decreases ETBF-induced inflammation in the large intestines of C57BL/6 mice. C57BL/6 female mice were inoculated with WT-ETBF (~1 × 109 CFU). HSD (4% and 8%) treated groups were given chow containing either 4% NaCl or 8% NaCl, respectively. C57BL/6 mice were sacrificed at day 18 post-infection. (A) Histology (H&E) of the cecum and distal colon, ×200 magnification; scale bar, 100 μm. (B) Inflammation scores of ceca. (C) Inflammation scores of distal colons. (D) Serum KC. (E) serum IL-17A. Each dot represents one mouse (n = 4–12 mice per group) in the scatterplots. The horizontal bar represents the median. * p < 0.05; *** p < 0.001; ns, no statistical significance.