Table 5.

Average values of the Rg and SASA of the simulated systems.

System	Rg* (nm)	SASA* (nm2)
Unligated Mpro	2.183 ± 0.0217	151.4341 ± 0.0236
Mpro-N3	2.181 ± 0.0213	155.3633 ± 0.0328
Mpro-lopinavir	2.185 ± 0.0228	151.2614 ± 0.0225
Mpro-amentoflavone	2.181 ± 0.0215	152.0211 ± 0.0216
Mpro-bilobetin	2.182 ± 0.0319	152.7821 ± 0.0326
Mpro-ginkgetin	2.181 ± 0.0311	153.6813 ± 0.0218

^*For obtaining the average value, 5 independent MD trajectories were analyzed with the aid of Rg and SASA.