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. 2020 Nov 3;25(21):5114. doi: 10.3390/molecules25215114

Table 5.

Checkerboard assays of each chitosan in combination with fluconazole against fluconazole-resistant clinical strains.

Drug-Resistant Strain Chitosan FICindex
C. albicans 3 kDa chitosan 0.375 ± 0.125
~15 kDa chitosan 0.188 ± 0.063
20–30 kDa chitosan 0.208 ± 0.168
LMW chitosan 0.16 ± 0.09
MMW chitosan 0.085 ± 0.015
C. tropicalis 3 kDa chitosan 0.19 ± 0.07
~15 kDa chitosan 0.26 ± 0.24
20–30 kDa chitosan 0.265 ± 0.235
LMW chitosan 0.26 ± 0.24
MMW chitosan 0.31 ± 0.19