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. 2020 Oct 29;21(21):8089. doi: 10.3390/ijms21218089
PD-L1 Programmed cell death ligand-1
PD-1 Programmed cell death protein-1
HNSCC Head and neck squamous cell carcinoma
siRNA Small interfering ribonucleic acid
EMT Epithelial–mesenchymal transition
FDA Food and Drug Administration
PD-L2 Programmed cell death ligand 2
IFN Interferon
APC Antigen-presenting cell
PCI Pittsburgh Cancer Institute
NT Nontargeting
KD Knockdown
CV Control vector
OE Overexpression
RAC2 Gene encoding for the small Rho-GTPase Rac2
ARGHDIA Gene encoding for Rho-GDP-dissociation inhibitor 1
PAK4 Gene encoding for serine/threonine-protein kinase PAK 4
ITGA4 Gene encoding for integrin alpha 4
MMP9 Gene encoding for matrix-metalloproteinase 9
RHO Gene encoding for the small Rho-GTPase Rho
qPCR Quantitative polymerase chain reaction
DMEM Dulbecco’s modified Eagle’s medium
FCS Fetal calf serum
EDTA Ethylenediaminetetraacetic acid
DAB 3,3′-Diaminobenzidine
PBS Phosphate buffered saline
PVDF Polyvinylidene fluoride
SDS-PAGE Sodium dodecyl sulfate polyacrylamide gel electrophoresis
γ Gamma
SD Standard deviation