Table 1.
Studies showing a relationship between SARS-CoV-2 infection and cardiovascular disease.
| Authors | Study Design | No. of Patients | Cardiovascular Involvement |
|---|---|---|---|
| [1] | Retrospective, multicentre study | 1099 | Comorbidity [2.5% of patients with CAD] |
| [6] | Retrospective | 41 | Comorbidity [15% of patients with CVD] and complication [12% of patients with acute cardiac injury; 31% admitted to ICU, 4% non ICU] |
| [24] | Retrospective, multicentre study | 8910 | Comorbidity associated with mortality [20% of patients non survivors with CAD, 5.6% with HF, 6.8% with arrhythmia] |
| [39] | Retrospective study | 416 | Complication associated with mortality [19.7% of patients with cardiac injury, mortality in patients with cardiac injury 51.2%] |
| [40] | Retrospective, multicentre study | 191 | Comorbidity [8% of patients with CAD] and mortality [24% of patient with CAD] |
| [41] | Retrospective, multicentre study | 355 | Comorbidity [30% of patients with ischemic heart disease, 24.5% of patients with atrial fibrillation] |
| [42] | Retrospective study | 99 | Comorbidity [40% of patients with CV and CBV diseases] |
| [56] | Retrospective case series | 138 | Comorbidity [14.5% of patients with CVD]. Complication [44.4% of patients admitted to ICU |
| [46] | Retrospective study | 193 | Comorbidity [16.1% of patients with CVD, 27.1% of diabetic patients with CVD] and mortality [25% of patients non survivors with CVD].Diabetes |
| [47] | Retrospective study | 174 | Comorbidity [32.4% of diabetic patients with CVD]. |
| [49] | Retrospective study | 28 | Comorbidity and outcome [ICU patients have higher levels of Troponin I] |
| [58] | Retrospective case series | 187 | Comorbidity [35.3% of patients with CVD, 27.8% of patients with myocardial injury] and mortality [13.33% of patients with CVD, 37.5% of patients with elevated levels of Troponin I, 69.44% of patients with CVD and elevated levels of Troponin I] |
| [60] | Retrospective study | 28 | Complication [STEMI as first presentation in 85.7% of cases] |
| [63] | Retrospective study | 21 | Complication [9.1% of patients with acute cardiac injury] |
| [59] | Case series | 54 | NT-proBNP associated with higher mortality |
| [72] | Case series | 21 | Comorbidity [42.9% of patients with congestive heart failure]. Complication [33.3% of patients develop cardiomyopathy] |
| [62] | Case series | 18 | Complication [STEMI] |
| [61] | Case report | 1 | Complication [STEMI] |
| [75] | Case report | 1 | Complication [myocarditis] |
| [76] | Case report | 1 | Complication [myocarditis] |
| [77] | Case report | 1 | Complication [myocarditis] |
| [80] | Case report | 1 | Complication [myocarditis] |
| [78] | Case report | 1 | Complication [myocarditis] |
| [81] | Case report | 1 | Complication [Tako-Tsubo syndrome] |
| [82] | Case report | 1 | Complication [Tako-Tsubo syndrome] |
| [83] | Case report | 1 | Complication [Tako-Tsubo syndrome] |
| [84] | Case report | 1 | Complication [Tako-Tsubo syndrome, atrial fibrillation] |