Table 6.
Lipid profile and biomarkers of understudy mice.
| Parameters | ND | HFD | HFD + 150 | HFD + 300 | HFD + Orlistat (50 mg/kg BW) |
|---|---|---|---|---|---|
| TC in mg/dL | 46.55 ± 1.87 a | 154.12 ± 5.45 e | 112.07 ± 3.55 d | 72.87 ± 2.03 c | 54.05 ± 2.05 b |
| HDL (mg/dL) | 25.66 ± 2.38 a | 85.50 ± 2.12 e | 61.27 ± 2.09 d | 38.04 ± 1.38 c | 32.55 ± 1.25 b |
| LDL (mg/dL) | 18.77 ± 0.73 a | 65.50 ± 3.84 e | 48.17 ± 3.22 d | 32.33 ± 0.95 c | 19.82 ± 0.75 a,b |
| Triglyceride (mg/dL) | 1.79 ± 0.03 b | 2.91 ± 0.08 d | 2.03 ± 0.02 b,c | 1.97 ± 0.04 b,c | 1.47 ± 0.03 a |
| Hb (g/dL) | 9.92 ± 0.11 a | 7.35 ± 0.15 e | 7.82 ± 0.09 d | 8.44 ± 0.13 b,c | 8.48 ± 0.11 b |
| ALT (U/L) | 25.25 ± 2.25 a | 80.05 ± 2.50 e | 72.10 ± 2.48 d | 45.39 ± 1.90 b,c | 42.84 ± 2.24 b |
| AST (U/L) | 40.12 ± 2.38 a | 76.24 ± 2.35 e | 63.98 ± 3.32 d | 51.11 ± 3.33 c | 47.35 ± 2.06 b |
Superscript (a–e) indicates significant difference of means (p < 0.05). Values not sharing a letter categorized as significantly different.