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. 2020 Oct 27;21(21):7962. doi: 10.3390/ijms21217962

Figure 1.

Figure 1

Cancer susceptibility gene 2 (CASC2) and miR-21 gene expression are associated with glioma malignancy grade. (A) CASC2 expression measured by RT-qPCR in RHB (reference human brain, n = 2), II-III malignancy grade gliomas (n = 17) and IV grade gliomas, n = 82 (glioblastomas). (B) miR-21 expression measured in the same patient postoperative tumor tissue by RT-qPCR in RHB (n = 4), II-III (n = 17) and IV grade (n = 66) gliomas. The lines in the graphs indicate mean with the SD. Color corresponds to different glioma malignancy grade: green—grade II, red—grade III, black—grade IV gliomas. Triangle shape corresponds to isocitrate dehydrogenase 1 mutated C. 395G > A (IDH1mut) glioma, circle shape—isocitrate dehydrogenase 1 wild-type (IDH1wt).