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Regulatory role of angiotensin-converting enzyme 2 in the pathogenesis of acute lung injury and ARDS. Increasing/decreasing activity of the angiotensin-converting enzyme 2 (ACE2) regulates the dynamic balance within the RAS. Ang II—angiotensin II; Ang A—angiotensin A; DABK—des-Arg9-bradykinin; Ang 1–7—angiotensin 1–7; Ang 1–9—angiotensin 1–9.
