Table 5.
Association between DRD2 polymorphism and sleep dysfunction.
| Genotype | n | Sleep Dysfunction |
Normal | OR (95% CI) | AOR a (95%CI) |
|---|---|---|---|---|---|
| rs1799732 | |||||
| Ins/Ins | 546 | 126 | 420 | Reference | Reference |
| Ins/Del | 139 | 33 | 106 | 1.04 (0.67–1.61) | 1.03 (0.66–1.62) |
| Del/Del | 8 | 1 | 7 | 0.48 (0.06–3.91) | 0.38 (0.04–3.40) |
| p-value for χ2 | 0.764 | ||||
| p-value for HWE | 0.458 | 0.915 | |||
| rs1800497 | |||||
| A2A2 | 259 | 43 | 216 | Reference | Reference |
| A1A2 | 317 | 72 | 245 | 1.48 (0.97–2.25) | 1.52 (0.99–2.33) |
| A1A1 | 117 | 45 | 72 | 3.14 (1.91–5.16) * | 2.90 (1.75–4.82) * |
| p-value for χ2 | <0.001 | ||||
| p-value for HWE | 0.207 | 0.848 |
OR, odds ratio; CI, confidence interval; HWE, Hardy–Weinberg equilibrium; * p < 0.05; a Adjusted odds ratios (AOR) for age, sex, job tenure, smoking and alcohol consumption.