Table 4.
Analgesic effect of methanol extract of A. montanum (MEAM) and diclofenac sodium (DS) on tail immersion test in mice.
| Treatment (mg/kg) | Response Times (s) (% MPE) | ||||
|---|---|---|---|---|---|
| 0 min | 30 min | 60 min | 90 min | 120 min | |
| Control | 3.13 ± 0.05 | 4.22 ± 0.15 | 4.25 ± 0.06 | 3.97 ± 0.06 | 3.83 ± 0.06 |
| DS 10 | 3.34 ± 0.03 | 6.27 ± 0.16 *** (17.59) | 7.49 ± 0.15 *** (24.93) | 7.55 ± 0.24 *** (25.27) | 6.82 ±0.05 *** (20.876) |
| MEAM 100 | 3.16 ± 0.04 | 3.95 ± 0.05 (4.75) | 4.99 ± 0.04 *** (10.90) | 5.34 ± 0.16 *** (12.96) | 5.08 ± 0.09 *** (11.38) |
| MEAM 200 | 3.17 ± 0.09 | 4.22 ± 0.17 (6.27) | 5.68 ± 0.19 *** (14.89) | 5.73 ± 0.17 *** (15.23) | 5.74 ± 0.32 *** (15.32) |
| MEAM 400 | 3.13 ± 0.05 | 5.35 ± 0.16 *** (13.15) | 6.57 ± 0.15 *** (20.41) | 7.36 ± 0.10 *** (25.09) | 6.93 ± 0.14 *** (22.58) |
MPE, maximal possible effect. *** p < 0.001, compared with vehicle control (Dunnett’s test).