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. 2020 Nov 5;25(21):5153. doi: 10.3390/molecules25215153

Table 4.

Analgesic effect of methanol extract of A. montanum (MEAM) and diclofenac sodium (DS) on tail immersion test in mice.

Treatment (mg/kg) Response Times (s) (% MPE)
0 min 30 min 60 min 90 min 120 min
Control 3.13 ± 0.05 4.22 ± 0.15 4.25 ± 0.06 3.97 ± 0.06 3.83 ± 0.06
DS 10 3.34 ± 0.03 6.27 ± 0.16 *** (17.59) 7.49 ± 0.15 *** (24.93) 7.55 ± 0.24 *** (25.27) 6.82 ±0.05 *** (20.876)
MEAM 100 3.16 ± 0.04 3.95 ± 0.05 (4.75) 4.99 ± 0.04 *** (10.90) 5.34 ± 0.16 *** (12.96) 5.08 ± 0.09 *** (11.38)
MEAM 200 3.17 ± 0.09 4.22 ± 0.17 (6.27) 5.68 ± 0.19 *** (14.89) 5.73 ± 0.17 *** (15.23) 5.74 ± 0.32 *** (15.32)
MEAM 400 3.13 ± 0.05 5.35 ± 0.16 *** (13.15) 6.57 ± 0.15 *** (20.41) 7.36 ± 0.10 *** (25.09) 6.93 ± 0.14 *** (22.58)

MPE, maximal possible effect. *** p < 0.001, compared with vehicle control (Dunnett’s test).