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. 2020 Nov 5;25(21):5153. doi: 10.3390/molecules25215153

Table 5.

Antipyretic effect of methanol extract of A. montanum (MEAM) on Brewer’s yeast induced pyrexia in mice.

Treatment (mg/kg) Basal Temp. (°F) 0 Hour (after 24 Hour) Rectal Temperature (°F)
1st Hour 2nd Hour 3rd Hour 4th Hour
Control 99.20 ± 0.16 101.02 ± 0.15 100.82 ± 0.11 100.61 ± 0.09 100.43 ± 0.11 100.20 ± 0.17
Paracetamol 100 98.82 ± 0.21 100.50 ± 0.16 * 99.98 ± 0.14 *** 99.52 ± 0.14 *** 99.13 ± 0.15 *** 98.61 ± 0.15 ***
MEAM 100 98.93 ± 0.17 100.04 ± 0.09 *** 99.82 ± 0.09 *** 99.60 ± 0.08 *** 99.40 ± 0.07 *** 99.02 ± 0.11 ***
MEAM 200 99.02 ± 0.15 100.47 ± 0.24 * 99.96 ± 0.18 *** 99.73 ± 0.19 *** 99.33 ± 0.14 *** 99.05 ± 0.20 ***
MEAM 400 98.97 ± 0.08 100.33 ± 0.14 ** 99.96 ± 0.18 *** 99.54 ± 0.10 *** 99.10 ± 0.11 *** 98.82 ± 0.09 ***

* p < 0.05, ** p < 0.01, *** p < 0.001, statistically significant in comparison to control (Dunnett’s test).