Comparison between IFG and each group of graded urine 8-OHdG levels in normoglycemic subjects. Normoglycemic subjects graded into three tertiles based on urine 8-OHdG levels and IFG state were compared regarding the factors correlating with high urine 8-OHdG and the mechanism of DPN. Urine 8-OHdG (a), PINT scores (b), age (c), body weight (d), FBG (e), HbA1c (f), Hs-CRP (g), LBP (h) and pentosidine (i) were evaluated. 8-OHdG, 8-hydroxy-2′-deoxyguanosine; L-8OH, 8-OHdG low; I-8OH, 8-OHdG intermediate; H-8OH, 8-OHdG high; IFG, impaired fasting glucose; Cr, creatinine; FBG, fasting blood glucose; Hs-CRP, high sensitive C-reactive protein; LBP, lipopolysaccharide-binding protein. Mean ± SEM, * p < 0.01 vs. L-8OH, †
p < 0.01 vs. I-8OH, ‡
p < 0.01 vs. H-8OH, §
p < 0.05 vs. H-8OH, #
p < 0.05 vs. L-8OH, ** p < 0.05 vs. I-8OH.