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. 2020 Oct 30;10:1583. doi: 10.3389/fonc.2020.01583

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Copyright © 2020 Cheng, Kong, Wang, Fang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of overall survival between patients receiving chemotherapy and those not receiving chemotherapy or unknown in the five age groups. (I, N) There were significant differences of overall survival in age group of 66–80 years with intermediate-risk RS (P = 0.031) and high-risk RS (P = 0.042). (E) Women >80 years with low-risk RS had worse overall survival when receiving chemotherapy than those not or unknown (P = 0.002). (J, O) Women aged >80 years with intermediate-risk and high-risk RS, chemotherapy also seemed to be harmful although the differences were not statistically significant (P > 0.05). (A–D, F–H, K–M) There were no significant difference in any other age groups (P > 0.05).