Table 1.
Characteristics | Overall (n = 49,539) | ≤ 35 years of age (n = 672) | 36–50 years of age (n = 12,474) | 51–65 years of age (n = 23,759) | 66–80 years of age (n = 12,160) | > 80 years of age (n = 474) |
---|---|---|---|---|---|---|
Age at diagnosing | ||||||
Median (range) | 58 (18–92) | 32 (18–35) | 46 (36–50) | 58 (51–65) | 70 (66–80) | 83 (81–92) |
Race (%) | ||||||
White | 40,413 (81.6) | 486 (72.3) | 9650 (77.4) | 19,580 (82.4) | 10,296 (84.7) | 401 (84.6) |
Black | 4,008 (8.1) | 84 (12.5) | 1,078 (8.6) | 1,851 (7.8) | 951 (7.8) | 44 (9.3) |
Others※ | 4,768 (9.6) | 96 (14.3) | 1,645 (13.2) | 2,157 (9.1) | 843 (6.9) | 27 (5.7) |
Unknown | 350 (0.7) | 6 (0.9) | 101 (0.8) | 171 (0.7) | 70 (0.6) | 2 (0.4) |
RS | ||||||
Mean (±SD) | 16.71 (8.66) | 19.62 (9.38) | 16.99 (8.13) | 16.84 (8.66) | 16.04 (9.05) | 15.84 (9.60) |
Median (range) | 16 (0–74) | 18 (0–65) | 16 (0–73) | 16 (0–74) | 15 (0–69) | 15 (0–55) |
RS risk group (TAILORx standard) (%) | ||||||
Low (0–10) | 11,164 (22.5) | 86 (12.8) | 2,309 (18.5) | 5,317 (22.4) | 3,313 (27.2) | 139 (29.3) |
Intermediate (11–25) | 31,731 (64.1) | 453 (67.4) | 8,602 (69.0) | 15,203 (64.0) | 7,208 (59.3) | 265 (55.9) |
High (26–100) | 6,644 (13.4) | 133 (19.8) | 1563 (12.5) | 3,239 (13.6) | 1,639 (13.5) | 70 (14.8) |
Histology-broad groupings (%) | ||||||
8500–8549: Ductal and lobular neoplasms | 47,799 (96.5) | 628 (93.5) | 1,2053 (96.6) | 22,969 (96.7) | 11,704 (96.3) | 445 (93.9) |
Others# | 1,740 (3.5) | 44 (6.5) | 421 (3.4) | 790 (3.3) | 456 (3.7) | 29 (6.1) |
Tumor size (%) | ||||||
T1 | 37,238 (75.2) | 481 (71.6) | 9,556 (76.6) | 18,153 (76.4) | 8,760 (72.0) | 288 (60.8) |
T2 | 11,316 (22.8) | 177 (26.3) | 2,696 (21.6) | 5,178 (21.8) | 3,107 (25.6) | 158 (33.3) |
T3/T4 | 757 (1.5) | 11 (1.6) | 174 (1.4) | 313 (1.3) | 234 (1.9) | 25 (5.3) |
TX (Unknown) | 228 (0.5) | 3 (0.4) | 48 (0.4) | 115 (0.5) | 59 (0.5) | 3 (0.6) |
Histological grades (%) | ||||||
I | 14,562 (29.4) | 155 (23.1) | 3,674 (29.5) | 7,222 (30.4) | 3,398 (27.9) | 113 (23.8) |
II | 26,416 (53.3) | 344 (51.2) | 6,666 (53.4) | 12,530 (52.7) | 6,613 (54.4) | 263 (55.5) |
III/IV | 7,564 (15.3) | 159 (23.7) | 1,913 (15.3) | 3,532 (14.9) | 1,874 (15.4) | 86 (18.1) |
Unknown | 997 (2.0) | 14 (2.1) | 221 (1.8) | 475 (2.0) | 275 (2.3) | 12 (2.5) |
Progesterone receptor status (%) | ||||||
Positive | 45,317 (91.5) | 642 (95.5) | 12,018 (96.3) | 21,435 (90.2) | 10,824 (89.0) | 398 (84.0) |
Negative/Borderline | 4,191 (8.4) | 30 (4.5) | 446 (3.6) | 2,308 (9.7) | 1,331 (10.9) | 76 (16.0) |
Unknown | 31 (0.1) | 0 (0.0) | 10 (0.1) | 16 (0.1) | 5 (0.1) | 0 (0.0) |
Chemotherapy records (%) | ||||||
Yes | 8,698 (17.6) | 276 (41.1) | 2,923 (23.4) | 4,193 (17.6) | 1,286 (10.6) | 20 (4.2) |
No/Unknown | 4,0841 (82.4) | 396 (58.9) | 9,551 (76.6) | 19,566 (82.4) | 10,874 (89.4) | 454 (95.8) |
American Indian/AK Native, Asian/Pacific Islander.
8000–8009: Unspecified neoplasms; 8010–8049: Epithelial neoplasms, NOS; 8050–8089: Squamous cell neoplasms; 8140–8389: Adenomas and adenocarcinomas; 8390–8429: Adnexal and skin appendage neoplasms; 8440–8499: Cystic, mucinous and serous neoplasms; 8560–8579: Complex epithelial neoplasms.