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. 2019 Aug 11;10(6):1241–1257. doi: 10.1002/jcsm.12474

Figure 3.

Figure 3

Effect of Fst288 overexpression on proteins involved in insulin signalling and glucose handling. Protein expression of (A) AKT2, (B) TBC1D4, (C) TBC1D1, (D) p70S6K, (E) PAK1, (F) IRS1, (G) GLUT4, (H) HKII, and (I) complexes of the electron transport chain in tibialis anterior muscle following 2 week rAAV6:Fst288 overexpression in muscle. No difference was observed in protein expression between the 10 min saline and insulin‐stimulated conditions, and thus, samples were pooled to increase statistical power and accuracy of effect‐size estimation (n = 12–14, one to two mouse samples excluded due to poor quality blot). (J) Representative blots. Statistically significant effect of Fst288 overexpression is indicated by **/*** P < 0.01/0.001. Data are shown as mean ± SEM with individual values.