Table 3.
Association Between Clinical Indicators in CAS Individuals and Cluster Assignment
| Clinical Variable | Cluster 1 (High severity) (n = 10) |
Cluster 2 (Moderate severity) (n = 11) |
Cluster 3 (Mild severity) (n = 10) |
Fisher exact P-value1 |
|---|---|---|---|---|
| Problems with Feeding Eating | 0.50 | 0.27 | 0 | 0.036 |
| Little vocal play or babbling | 0 | 0.18 | 0.20 | 0.511 |
| Family history of communication disorders | 1 | 0.91 | 1 | 0.999 |
| Delayed language onset | 0.50 | 0.73 | 0.80 | 0.398 |
| Gross motor incoordination | 0.30 | 0.27 | 0.30 | 0.999 |
| Fine motor incoordination | 0.50 | 0.18 | 0.20 | 0.298 |
| Body dyspraxia body awareness in space | 0.10 | 0.09 | 0 | 0.999 |
| “Soft” neurological signs | 0.10 | 0.27 | 0 | 0.289 |
| Sensory processing issues | 0.20 | 0 | 0.20 | 0.353 |
| Dysarthria | 0.10 | 0.27 | 0.20 | 0.849 |
| Limited repertoire of sounds | 0.20 | 0.64 | 0.50 | 0.128 |
Values shown are proportion with the trait. “n” is the number of CAS individuals per cluster. p-values shown are not adjusted for multiple testing. 1Test of association is across CAS clusters 1,2 and 3 only