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Incomplete Synapsis of the Homologous Chromosome Synapsis during In Vitro Meiosis
Unsynapsed homologous chromosomes marked with γH2AX (A) or ATR (B) remain in in vitro-generated pachytene-like spermatocytes stained for SYCP3 (green), γH2AX or ATR (red), centromeres (CREST, white), and DNA (DAPI, blue in merged images). Regions inside dashed boxes are shown at higher magnification in the following image. Scale bars, 5 μm.
