Fig. 1.

Impaired pattern separation of App-KI mice in the LD task. a Diagram represents location discrimination tasks with a medium degree of separation between stimuli, as well as criteria for phase change. b, c, Number of phase changes in LDm training sessions in App-KI mice (n = 17). Mice were given a maximum of 62 trials/session/d for 10 days. Data are presented as means ± SEM. *, † p < 0.05 vs control. d Diagram represents location discrimination tasks with high and low degree of separation between stimuli, as well as criteria for phase change. e Number of phase changes during 30-min training sessions in App-KI mice (n = 17). Data are presented as means ± SEM. *p < 0.05 vs LDl in control