Table 1.
Clinical and laboratory characteristics in all subjects
| Characteristics | AIS (n = 566) | Controls (n = 197) | P value * |
|---|---|---|---|
| Age (years) | 66 (57, 77) | 67 (51, 76) | 0.114 |
| Sex (M/F) | 318/248 | 91/106 | 0.016 * |
| BMI (kg/m2) | 24.4 (22.4, 27.4) | 23.4 (21.4, 25.3) | < 0.001 * |
| Smoking (%) | 75 (13.3) | 19 (9.6) | 0.209 |
| Alcohol use (%) | 78 (13.8) | 18 (9.1) | 0.105 |
| H-type hypertension (%) | 103 (18.2) | 18 (9.1) | 0.002 * |
| Hypertension (%) | 430 (76.0) | 79 (40.1) | < 0.001 * |
| Diabetes mellitus (%) | 155 (27.4) | 17 (8.6) | < 0.001 * |
| Metabolic syndrome (%) | 115 (20.3) | 27 (13.7) | 0.043 * |
| Cardiovascular disease (%) | 464 (82.0) | 83 (42.1) | < 0.001 * |
| SBP (mmHg) | 139.5 (127, 156) | 123 (121, 140) | < 0.001 * |
| DBP (mmHg) | 84 (77, 94) | 78 (70, 87) | < 0.001 * |
| GLU (mmol/L) | 5.3 (4.7, 6.2) | 5.2 (4.7, 6.1) | 0.343 |
| SCr (μmol/L) | 69.9 (59, 83) | 63 (53, 74) | < 0.001 * |
| TC (mmol/L) | 4.2 (3.5, 5.1) | 4.2 (3.5, 4.9) | 0.228 |
| LDL-C (mmol/L) | 2.5 (1.9, 3.1) | 2.3 (1.8, 2.8) | 0.003 * |
| HDL-C (mmol/L) | 1.1 (0.8, 1.3) | 1.2 (0.9, 1.6) | < 0.001 * |
| TG (mmol/L) | 1.4 (1.0, 2.1) | 1.2 (0.9, 1.5) | < 0.001 * |
| ApoA (mmol/L) | 1.2 (1.1, 1.4) | 0.9 (0.8, 1.2) | < 0.001 * |
| ApoB (mmol/L) | 0.8 (0.6, 0.9) | 0.8 (0.6, 0.9) | 0.494 |
| sd-LDL (mg/dL) | 7 (2, 17) | 3 (1, 6) | < 0.001 * |
AIS Acute ischemic stroke, M Male, F Female, BMI Body mass index, SBP Systolic blood pressure, DBP Diastolic blood pressure, GLU Fasting blood glucose, Scr Serum creatinine, TC Total cholesterol, LDL-C Low density lipoprotein cholesterol, HDL-C High density lipoprotein cholesterol, TG Triglyceride, ApoA Apolipoprotein A, ApoB Apolipoprotein B, sd-LDL Small dense LDL; *p < 0.05