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. 2020 Aug 10;19(11):1749–1759. doi: 10.1074/mcp.RP120.002128

Fig. 4.

Fig. 4.

Functional annotation of the differentially-expressed proteins in early SARS-CoV-2 infection. A, B, and C, are the significantly altered signaling pathway, protein domain, and cellular component identified by antibody microarrays in early-stage COVID-19, respectively. P-values were calculated by two-sided hypergeometric test based on the KEGG/Reactome/InterPro database and GO terms. Up-regulated and down-regulated pathways are indicated in red (right) and blue (left) bars.