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Associations of a variant in KCNMA1 with disability and spinal cord damage of NMOSD. (A) Manhattan plot of association signals with rank‐normalized EDSS scores adjusted for age of onset and disease duration. A peak association (rs1516512) was located in KCNMA1 of chromosome 10. (B) Box‐whisker plot of raw EDSS scores in each rs1516512 allele carrier. (C) Frequency of transverse myelitis in each rs1516512 allele carrier. TM, transverse myelitis.
