Table 1.
Summary of clinical and pathological findings in autopsied NMOSD cases.
| Autopsy | Age (yrs) | Sex |
Disease duration (yrs) |
Clinically estimated lesion sites 1 | Pathologically determined lesion sites 1 | Neurological symptom possibly associated with death |
|---|---|---|---|---|---|---|
| NMOSD‐1 | 88 | M | 0.4 | S1 | O, S | Paraplegia |
| NMOSD‐2 2 | 37 | F | 17.0 | O8, Bs1, S9, Cr3 | Bs, S, Cr | Quadriplegia |
| NMOSD‐3 | 54 | F | 4.0 | O1, S6 | O, S | Bulbar palsy |
Abbreviations: Bs, brainstem; Cl, cerebellum; Cr, cerebrum, F, female; M, male; NMOSD, neuromyelitis optica spectrum disorders; O, optic nerve; S, spinal cord.
1
Numbers indicate exacerbations in each lesion site (for example, O2 represents two optic neuritis episodes).
2
A NMOSD case seropositive for anti‐AQP4 antibody.