Table 4.
Association between urinary 8-OHdG levels and atopic phenotypes restricted to participants with atopic dermatitis (n = 200).
| Urinary 8-OHdG Levels (ng/mg Cr) | Total | Number of Atopic Phenotypes (%) | Adjusted OR | p-Value |
|---|---|---|---|---|
| n = 200 | (95% CI) | |||
| Asthma | 0.02 | |||
| Q1: <17.68 | 50 | 16 (32.0%) | 1 (reference) | |
| Q2: 17.68–26.38 | 50 | 14 (28.0%) | 1.17 (0.47–2.89) | |
| Q3: 26.38–42.7 | 50 | 8 (16.0%) | 1.02 (0.40–2.60) | |
| Q4: >42.7 | 50 | 11 (22.0%) | 2.71 (1.14–6.43) | |
| Allergic rhinitis | 0.05 | |||
| Q1: <17.68 | 50 | 32 (64.0%) | 1 (reference) | |
| Q2: 17.68–26.38 | 50 | 28 (56.0%) | 1.10 (0.49–2.49) | |
| Q3: 26.38–42.7 | 50 | 19 (38.0%) | 1.39 (0.61–3.20) | |
| Q4: >42.7 | 50 | 20 (40.0%) | 2.13 (0.93–4.89) | |
| Night pruritus | 0.18 | |||
| Q1: <17.68 | 50 | 21 (42.0%) | 1 (reference) | |
| Q2: 17.68–26.38 | 50 | 18 (36.0%) | 1.08 (0.46–2.54) | |
| Q3: 26.38–42.7 | 50 | 16 (32.0%) | 1.13 (0.48–2.68) | |
| Q4: >42.7 | 50 | 16 (32.0%) | 2.20 (0.95–5.09) |
Abbreviations: CI, confidence interval; OR, odd ratio; (ng/mg Cr), nanograms per milligram of creatinine; Q1: 0–25th percentiles; Q2: 25–50th percentiles; Q3: 50–75th percentiles; Q4: >75th percentiles; OR was adjusted by age, gender, daycare <1-year-old, preterm birth <37 weeks, family income (<USD $20,000/USD $20,000–33,300/≥USD $33,300), duration of breast feeding <6 months/≥6 months), tobacco smoke exposure during pregnancy, and parental history of atopy.