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. 2020 Nov 7;21(21):8355. doi: 10.3390/ijms21218355

Figure 4.

Figure 4

Activity of compounds on chikungunya virus (CHIKV) infection and viability of baby hamster kidney (BHK) 21 cells. BHK 21 cells were infected with CHIKV nanoluc and simultaneously treated with the compound. After 16 h post-infection (p.i.), cells were lysed, and a Renilla luciferase assay was performed to assess CHIKV replication rates. In parallel, a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay was performed. Mean values of a minimum of three independent experiments each measured in triplicate are represented. **** p < 0.001/* p < 0.05 were considered significant.