. 2020 Nov 13;284:103585. doi: 10.1016/j.resp.2020.103585

Table 2.

Univariate and multivariate logistic regression of potential predictive parameters at intensive care unit admission for non-invasive ventilation failure (only converged models are reported). β indicates regression coefficients; CI, confidence intervals; OR, odds ratio; PaO₂/FiO₂, ratio of arterial oxygen pressure to inspired oxygen fraction breathing room air; CT, chest tomography; HU, Hounsfield Units; DTF, diaphragmatic thickening fraction.

Parameter	Univariate analysis				Multivariate analysis
	β	OR	95 %CI	p	β	OR	95 %CI	p
Age (years)	0.021	1.021	0.947 - 1.111	0.598	Not entered
Sex (F)	−0.827	0.438	0.044 - 4.247	0.454	Not entered
SAPS	0.072	1.075	0.958 - 1.227	0.222	Not entered
Temperature	−0.904	0.405	0.088 - 1.554	0.320	Not entered
SpO₂	−0.000	1.000	0.996 - 1.002	0.728	Not entered
Heart rate	0.022	1.002	0.975 - 1.076	0.362	Not entered
Respiratory rate	0.452	1.572	1.128 - 2.498	<0.001	0.588	1.800	1.032 - 10.999	0.105
Systolic blood pressure	0.011	1.011	0.964 - 1.066	0.649	Not entered
Diastolic blood pressure	−0.023	0.977	0.913 - 1.038	0.460	Not entered
PaO₂/FiO₂ ratio	−0.004	0.996	0.980 - 1.012	0.641	Not entered
P_aO₂	0.019	1.019	0.979 - 1.064	0.353	Not entered
HCO₃	0.045	1.046	0.842 - 1.303	0.679	Not entered
Lactate	0.765	2.148	0.681 - 11.696	0.197	Not entered
CT Mean lung density	0.009	1.009	0.998 - 1.024	0.113	Not entered
DTF	−0.396	0.673	0.447 - 0.837	<0.001	−0.384	0.681	0.350 - 0.875	<0.001

B, regression coefficients; CI, confidence intervals; OR, odds ratio; PaO2/FiO2, ratio of arterial oxygen pressure to inspired oxygen fraction breathing room air; CT, chest tomography; DTF, diaphragmatic thickening fraction.