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. 2020 Nov 13;284:103585. doi: 10.1016/j.resp.2020.103585

Table 2.

Univariate and multivariate logistic regression of potential predictive parameters at intensive care unit admission for non-invasive ventilation failure (only converged models are reported). β indicates regression coefficients; CI, confidence intervals; OR, odds ratio; PaO2/FiO2, ratio of arterial oxygen pressure to inspired oxygen fraction breathing room air; CT, chest tomography; HU, Hounsfield Units; DTF, diaphragmatic thickening fraction.

Parameter Univariate analysis Multivariate analysis
β OR 95 %CI p β OR 95 %CI p
Age (years) 0.021 1.021 0.947 - 1.111 0.598 Not entered
Sex (F) −0.827 0.438 0.044 - 4.247 0.454 Not entered
SAPS 0.072 1.075 0.958 - 1.227 0.222 Not entered
Temperature −0.904 0.405 0.088 - 1.554 0.320 Not entered
SpO2 −0.000 1.000 0.996 - 1.002 0.728 Not entered
Heart rate 0.022 1.002 0.975 - 1.076 0.362 Not entered
Respiratory rate 0.452 1.572 1.128 - 2.498 <0.001 0.588 1.800 1.032 - 10.999 0.105
Systolic blood pressure 0.011 1.011 0.964 - 1.066 0.649 Not entered
Diastolic blood pressure −0.023 0.977 0.913 - 1.038 0.460 Not entered
PaO2/FiO2 ratio −0.004 0.996 0.980 - 1.012 0.641 Not entered
PaO2 0.019 1.019 0.979 - 1.064 0.353 Not entered
HCO3 0.045 1.046 0.842 - 1.303 0.679 Not entered
Lactate 0.765 2.148 0.681 - 11.696 0.197 Not entered
CT Mean lung density 0.009 1.009 0.998 - 1.024 0.113 Not entered
DTF −0.396 0.673 0.447 - 0.837 <0.001 −0.384 0.681 0.350 - 0.875 <0.001

B, regression coefficients; CI, confidence intervals; OR, odds ratio; PaO2/FiO2, ratio of arterial oxygen pressure to inspired oxygen fraction breathing room air; CT, chest tomography; DTF, diaphragmatic thickening fraction.