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. 2020 Oct 29;12:590168. doi: 10.3389/fnagi.2020.590168

TABLE 3.

Intervention-related changes in secondary outcomes.

AE vs Controls CCT vs Control COMB vs Control
B (95%CI), B (95%CI), B (95%CI),
SMD, p-value SMD, p-value SMD, p-value
Phsycological health and daily activitya
GDS 0.03 (−0.87, 0.93),
SMD = 0.01, p = 0.940
0.14 (−0.80, 1.08),
SMD = 0.04, p = 0.769
−0.30 (−1.30, 0.70),
SMD = −0.08, p = 0.554
VAMS −0.14 (−0.95, 0.67),
SMD = −0.04, p = 0.731
−0.21 (−1.03, 0.60),
SMD = −0.06, p = 0.605
−0.29 (−1.17, 0.58),
SMD = −0.08, p = 0.508
S-IQCODE 0.66 (−0.83, 2.15),
SMD = 0.12, p = 0.380
−1.27 (−2.79, 0.26),
SMD = −0.22, p = 0.101
−0.77 (−2.50, 0.96),
SMD = −0.13, p = 0.377
PSQI 0.74 (−0.56, 2.04),
SMD = 0.15, p = 0.261
1.49 (0.16, 2.82),
SMD = 0.30, p = 0.028*
1.01 (−0.41, 2.43),
SMD = 0.19, p = 0.161
Total CORE-OM −1.98 (−5.15, 1.18),
SMD = −0.17, p = 0.216
−1.17 (−4.44, 2.11),
SMD = −0.10, p = 0.480
−2.60 (−6.05, 0.86),
SMD = −0.20, p = 0.139
    Well-being CORE-OM −0.96 (−2.17, 0.26),
SMD = −0.23, p = 0.123
−0.90 (−2.17, 0.36),
SMD = −0.21, p = 0.158
−0.58 (−1.90, 0.75),
SMD = −0.13, p = 0.389
    Problems CORE-OM −1.25 (−2.84, 0.33),
SMD = −0.21, p = 0.120
−0.40 (−2.02, 1.23),
SMD = −0.07, p = 0.628
−1.11(−2.85, 0.62),
SMD = −0.17, p = 0.205
    Functioning CORE-OM 0.02 (−1.39, 1.42),
SMD = 0.00, p = 0.980
0.38 (−1.06, 1.82),
SMD = 0.07, p = 0.600
−0.73 (−2.26, 0.80),
SMD = −0.12, p = 0.344
    Risk CORE-OM 0.10 (−0.18, 0.38),
SMD = 0.09, p = 0.473
−0.14 (−0.42, 0.13),
SMD = −0.13, p = 0.300
−0.07 (−0.37, 0.22),
SMD = −0.06, p = 0.619
Physical activity and cardiorespiratory fitnessb
S-PA 4515.46 (3611.44, 5419.49),
SMD = 0.83, p < 001***
17.07 (−917.10, 951.24),
SMD = 0.00, p = 0.971
4214.04 (3214.97, 5213.12),
SMD = 0.71, p < 001***
NS-PA 1797.55 (−1316.63, 4911.72),
SMD = 0.17, p = 0.254
1947.28 (−1261.49, 5156.04),
SMD = 0.17, p = 0.230
1864.36 (−1524.03, 5252.74),
SMD = 0.16, p = 0.276
CRF 7.63 (3.93, 11.33),
SMD = 0.49, p < 001***
2.12 (−1.59, 5.82),
SMD = 0.13, textitp = 0.258
4.75 (0.73, 8.78),
SMD = 0.29, p = 0.021*

Note: AE, aerobic exercise group; CCT, computerized cognitive training; COMB, combined group; S-PA, sportive physical activity; NS-PA, non-sportive physical activity; Total-PA, total physical activity; CRF, cardiorespiratory fitness; GDS, Geriatric Depression Scale; VAMS, Modified Version of Visual Analog Mood Scale; S-IQCODE, Short Informant Questionnaire on Cognitive Decline in the Elderly; PSQI, Pittsburg Sleep Quality Index; CORE-OM, Clinical Outcome in Routine Evaluation-Outcome Measure.

SMD = β. aNegative SMD values favor AE or CCT or COMB vs Control group. bPositive SMD values favor AE or CCT or COMB vs Control group. Covariates: sex, age, years of education, and baseline. *p < 0.05. ***p < 0.001.