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. 2020 Oct 27;20(6):269. doi: 10.3892/etm.2020.9399

Figure 5.

Figure 5

DMF promotes Nrf2/HO-1 and PI3K/Akt signaling pathways in nucleus pulposus cells. Immunofluorescence staining results of (A) Nrf2 and (B) HO-1 (magnification, 400x). (C) Western blot and reverse transcription quantitative-PCR results of (D) Nrf2, (E) HO-1 and (F) Akt. *P<0.05 vs. the control group, #P<0.05 vs. the IL-1β group. DMF, dimethyl fumarate; Nrf2, erythroid 2-related factor; HO-1, heme oxygenase 1; p-, phosphorylated.