Figure 3.

SKI-II and EX527 induce apoptosis arrest in leukemia cells. Apoptosis was analyzed by PI and Annexin V staining. (A) K562 cells were treated with DMSO, 20 µM SKI-II, 20 µM EX527 or 20 µM SKI-II + 20 µM EX527 for 24 h. (B) KCL22 cells were treated with DMSO, 20 µM SKI-II, 20 µM EX527 or 20 µM SKI-II + 20 µM EX527 for 24 h. Data are presented as the means ± standard deviation. ^*P<0.05 and ^***P< 0.001 compared with DMSO. PI, propidium iodide.