Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov 7;21(21):8361. doi: 10.3390/ijms21218361

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Effect of 1 h PFF on F-actin distribution at the cell boundary, and schematic summary of the changes induced by PFF in MC3T3-E1 osteoblasts. (A) F-actin was visualized using phalloidin. Upper image: control cell. Lower image: PFF-treated cell. Bar = 25 µm. (B) PFF was sensed through integrins, which formed clusters of α and β-integrins. Paxillin changed from granular to short rods. F-actin was neatly arranged, and F-actin fluorescence intensity was increased by PFF. The morphology and volume of the cell body and nucleus changed in response to PFF, which might result in changed cell function. CON, control; PFF, pulsating fluid flow.