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. 2020 Nov 7;21(21):8362. doi: 10.3390/ijms21218362

Table 5.

Recently reported miRNAs in HCC therapy resistance.

Drug miRNA Target Reference
Cisplatin miR-33a-5p SOCS3 [220,221]
miR-363 MCL1 [223]
Doxorubicin miR-133a ABC subfamily C1 [224]
miR-326 ABC subfamily C1 [224]
5-FU miR-141 Kelch-like ECH-associated protein 1 (KEAP1),
Nuclear factor erythroid 2 like 2 (NFE2L2)
[225]
miR-125b BCL2 [14]
miR-195 BCL2 [14]
miR-503 eukaryotic translation initiation factor 4E (EIF4E) [228]
Sorafenib miR-93 p21Cip/Waf1 [222]
miR-181 Ras association domain family 1 (RASSF1) [230]
miR-216a p21Cip/Waf1 [222]
miR-217 p21Cip/Waf1 [222]
miR-494 PTEN, mTOR [231]