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. 2020 Nov 9;25(21):5200. doi: 10.3390/molecules25215200

Table 1.

The commonly used deubiquitinases (DUBs) for UbiCRest [15,16].

DUBs (Favored Ub Linkages)
USP21 (non-specific)
vOTU (non-specific, except M1)
OTUD3 (K6, K11)
Cezanne (K11)
OTUD2 (K11, K27, K29, K33)
TRABID (K29, K33, K63)
OTUB1 (K48)
OTUD1, AMSH (K63)
OTULIN (M1)

Note: USP21, vOTU are used as controls to digest most ubiquitin chains.