Table 2.
Viability of macrophages after exposure to amiodarone (Amio) or chloroquine (Chloro) compared to the respective solvent controls dimethylsulfoxide (DMSO) and aqua dest (AD). Abbreviations GM-MDM, M1 macrophages; M-MDM, M2 macrophages.
| Treatment | DMBM-2 | J774 | RAW264.7 | THP-1 | GM-MDM | M-MDM |
|---|---|---|---|---|---|---|
| DMSO | 100 ± 5 | 100 ± 2 | 100 ± 3 | 100 ± 5 | 100 ± 9 | 100 ± 2 |
| Amio2.5 | 98 ± 3 | 100 ± 1 | 103 ± 4 | 86 ± 3 | 92 ± 7 | 101 ± 9 |
| Amio5.0 | 107 ± 3 | 105 ± 3 | 111 ± 2 | 89 ± 3 | 89 ± 7 | 123 ± 11 |
| Amio7.5 | 104 ± 2 | 108 ± 2 | 107 ± 3 | 93 ± 6 | 97 ± 8 | 137 ± 2 |
| Amio10.0 | 90 ± 4 | 111 ± 2 | 115 ± 2 | 105 ± 3 | 96 ± 9 | 150 ± 3 |
| AD | 100 ± 5 | 100 ± 1 | 100 ± 2 | 100 ± 4 | 100 ± 5 | 100 ± 12 |
| Chloro2.5 | 97 ± 6 | 99 ± 1 | 102 ± 2 | 97 ± 10 | 97 ± 8 | 99 ± 9 |
| Chloro5.0 | 99 ± 3 | 107 ± 2 | 104 ± 5 | 92 ± 5 | 96 ± 7 | 95 ± 11 |
| Chloro7.5 | 99 ± 7 | 108 ± 3 | 102 ± 4 | 91 ± 5 | 97 ± 7 | 108 ± 6 |
| Chloro10.0 | 98 ± 5 | 111 ± 4 | 107 ± 4 | 97 ± 6 | 99 ± 4 | 131 ± 5 |