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. 2020 Nov 9;21(21):8389. doi: 10.3390/ijms21218389

Figure 5.

Figure 5

Figure 5

Comet assay showing the induction of DNA damage in MEF cells. (a) Representative fluorescent microscope images of untreated MEF cells and comet tails in treated MEF cells. (be) Induction of DNA damage in MEF cells treated with 24 h post-IR exosomes, (fh) 15 day post-IR exosomes obtained from organs, and plasma of 2 Gy WBI or PBI mouse compared DNA damage in MEF cells treated with exosomes obtained from unirradiated mouse organ exosomes. Percentage of DNA in the comet tail was scored in 200 cells treated for each group. Statistical analysis was performed using the Mann–Whitney U Test (* p < 0.05, ** p < 0.01, *** p < 0.001).