Table 1.
Demographic and clinical characteristics of healthy controls and BA patients.
| Variables | Healthy controls (n = 56) | BA patients (n = 96) | P-value |
|---|---|---|---|
| Gender (male:female) | 32:24 | 50:46 | 0.55 |
| Age (years) | 8.92 ± 0.47 | 10.00 ± 6.17 | 0.59 |
| BMI (kg/m2) | 15.78 ± 2.19 | 17.23 ± 3.07 | 0.53 |
| Liver stiffness (kPa) | 4.05 ± 0.11 | 31.02 ± 2.38 | < 0.001* |
| AST (IU/L) | 27.12 ± 0.89 | 133.72 ± 9.90 | < 0.001* |
| ALT (IU/L) | 9.16 ± 0.75 | 127.04 ± 9.12 | < 0.001* |
| ALP (IU/L) | – | 425.85 ± 34.05 | NA |
| Albumin (g/dL) | – | 4.07 ± 0.84 | NA |
| TB (mg/dL) | – | 2.01 ± 1.41 | NA |
| DB (mg/dL) | – | 1.70 ± 1.32 | NA |
| Platelet (cells/m3) | – | 162,409.00 ± 94,692.86 | NA |
| PT (s) | – | 12.44 ± 1.32 | NA |
| PTT (s) | – | 29.83 ± 2.88 | NA |
| APRI | – | 2.87 ± 2.07 | NA |
| INR | – | 1.09 ± 0.12 | NA |
*Difference is considered statistically significant at P-value less than 0.05 (two-tailed).
ALP alkaline phosphatase, ALT alanine aminotransferase, APRI AST to platelet ratio index, AST aspartate aminotransferase, BA biliary atresia, BMI body mass index, DB direct bilirubin, INR international normalized ratio, PT prothrombin time, PTT partial thromboplastin time, TB total bilirubin, NA not available.