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. 2020 Nov 12;10:19674. doi: 10.1038/s41598-020-76669-z

Table 3.

Multivariable Cox regression analysis for cardiovascular events after multiple imputation.

Variables Hazard ratio 95% Confidence interval p value
Myocardial infarction
Restfulness from sleep good 0.89 0.83–0.95  < 0.001
Age, years 1.06 1.06–1.07  < 0.001
Sex (man) 2.43 2.20–2.68  < 0.001
Obesity 1.26 1.15–1.38  < 0.001
High waist circumference 1.06 0.97–1.17 0.213
Hypertension 1.71 1.58–1.84  < 0.001
Diabetes mellitus 1.67 1.51–1.85  < 0.001
Dyslipidemia 1.65 1.54–1.78  < 0.001
Cigarette smoking 1.88 1.75–2.01  < 0.001
Alcohol drinking 0.66 0.62–0.72  < 0.001
Angina pectoris
Restfulness from sleep good 0.85 0.83–0.87  < 0.001
Age, years 1.05 1.05–1.05  < 0.001
Sex (man) 1.09 1.06–1.12  < 0.001
Obesity 1.11 1.07–1.15  < 0.001
High waist circumference 1.15 1.11–1.19  < 0.001
Hypertension 1.57 1.53–1.62  < 0.001
Diabetes mellitus 1.34 1.29–1.40  < 0.001
Dyslipidemia 1.21 1.18–1.24  < 0.001
Cigarette smoking 1.04 1.01–1.07 0.003
Alcohol drinking 0.94 0.92–0.97  < 0.001
Stroke
Restfulness from sleep good 0.85 0.82–0.88  < 0.001
Age, years 1.07 1.07–1.08  < 0.001
Sex (man) 0.98 0.94–1.02 0.318
Obesity 1.05 0.99–1.10 0.091
High waist circumference 1.04 0.99–1.09 0.129
Hypertension 1.90 1.82–1.97  < 0.001
Diabetes mellitus 1.35 1.27–1.43  < 0.001
Dyslipidemia 1.10 1.06–1.14  < 0.001
Cigarette smoking 1.27 1.22–1.32  < 0.001
Alcohol drinking 1.01 0.97–1.05 0.676
Heart failure
Restfulness from sleep good 0.86 0.84–0.88  < 0.001
Age, years 1.05 1.05–1.05  < 0.001
Sex (man) 1.04 1.01–1.07 0.004
Obesity 1.19 1.15–1.23  < 0.001
High waist circumference 1.13 1.09–1.17  < 0.001
Hypertension 1.94 1.89–1.99  < 0.001
Diabetes mellitus 1.32 1.27–1.38  < 0.001
Dyslipidemia 1.08 1.06–1.11  < 0.001
Cigarette smoking 1.08 1.05–1.11  < 0.001
Alcohol drinking 0.97 0.94–0.99 0.013
Atrial fibrillation
Restfulness from sleep good 0.93 0.89–0.97 0.002
Age, years 1.08 1.08–1.08  < 0.001
Sex (Man) 2.38 2.24–2.54  < 0.001
Obesity 1.09 1.02–1.16 0.008
High waist circumference 1.35 1.27–1.44  < 0.001
Hypertension 1.57 1.50–1.66  < 0.001
Diabetes mellitus 1.12 1.03–1.21 0.008
Dyslipidemia 0.83 0.79–0.87  < 0.001
Cigarette smoking 0.99 0.94–1.04 0.727
Alcohol drinking 1.16 1.11–1.22  < 0.001

Multivariable Cox regression analysis for cardiovascular events after multiple imputation showed that good restfulness from sleep was independently associated with the lower incidence of cardiovascular events including myocardial infarction, angina pectoris, stroke, heart failure, and atrial fibrillation.