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. 2020 Nov 12;10:19614. doi: 10.1038/s41598-020-76256-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Synergistic combination effect of macrolactin A and C14 surfactin against S. aureus ATCC 33592 (methicillin-resistant MRSA strain). Dose–response of macrolactin A without surfactin (black cross) is compared with increasing sub-MIC concentrations of surfactin C14 (0.5–2 µg/mL surfactin, light grey to black dots). Data is depicted as average values ± standard deviations from four independent experiments, n = 4.