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. 2020 Nov 12;10:19648. doi: 10.1038/s41598-020-76748-1

Table 3.

Relationship between various proteins in the amniotic fluid and spontaneous preterm delivery at < 34 weeks or ≤ 14 days of sampling in women with preterm labor without infection and/or inflammation, analyzed by multiple logistic regressions.

Variables Spontaneous preterm delivery < 34 weeks Spontaneous preterm delivery within 14 days
Adjusted a P-value b Adjusted c P-value d
AF FCGBP (ng/mL) 1.041 (1.001–1.082) 0.046 1.048 (1.006–1.091) 0.025
AF IGFBP-4 (ng/mL) 1.002 (1.000–1.005) 0.065
AF lipocalin-2 (ng/mL) 1.002 (1.000–1.003) 0.035 1.001 (0.999–1.002) 0.549
AF VEGFR-1 (ng/mL) 0.998 (0.996–1.000) 0.042 0.997 (0.995–1.000) 0.029

AF, amniotic fluid; FCGBP, Fc fragment of IgG binding protein; IGFBP, insulin-like growth factor-binding protein; VEGFR-1, vascular endothelial growth factor receptor 1.

aAdjustment for nulliparity and AF interleukin-6 levels. b For the adjusted odds ratio. c Adjustment for AF interleukin-6 levels. d For the adjusted odds ratio.