Table 1.
Genomic test designed to assess the risk of recurrence in BC.
| Test | Number of Genes/Proteins/Parameters | Lymph Node Involvement | Prognostic/Predictive Value | Recommendations | References |
|---|---|---|---|---|---|
| OncotypeDx (Genomic Health, Inc.) | 21 genes | N0 | +/+ | ASCO, ESMO, NCCN, St. Gallen | [32,33,34,35,36,37] |
| MAGEE (Agendia BV) | 6 parameters | N0 | +/+ | - | [38] |
| IHC4 | 4 proteins | N0 | +/+ | - | [39,40] |
| MammaPrint | 70 genes | N0-1 | +/+ | ESMO, St.Gallen | [32,34,41,42,43] |
| Breast Cancer Index (Bio Theranostics) | 5 genes + 2 biomarkers | N0 | +/+ | - | [40] |
| Prosigna PAM 50 (Nanostring) | 50 genes | N0 | +/− | St.Gallen | [32,44] |
| EndoPredict (Sividon Diagnostics) | 12 genes | N0-1 | +/+ | St. Gallen | [32,45] |